Girl in need of bone marrow highlights shortage of mixed-race donors

Posted in Articles, Health/Medicine/Genetics, Media Archive, United States on 2015-09-14 00:40Z by Steven

Girl in need of bone marrow highlights shortage of mixed-race donors

The Chicago Tribune
2015-09-13

Vikki Ortiz Healy

When doctors told Michelle Trujillo in July that her 6-year-old daughter would need a bone marrow transplant to save her life, the Crystal Lake mother didn’t want to wait another minute before getting her only child back to health.

But months later, Sophia — who has aplastic anemia, a rare disorder that impairs her immunity — is still waiting for a donor match. Meanwhile, Trujillo says she lies in bed at night making mental lists of places to try to find a donor with similar multiracial heritage to her daughter’s — a group with a strikingly low match rate.

“I don’t sleep at night. I think of, ‘What can I do now? Who can I contact now?’ ” said Trujillo, whose daughter is half Filipino, as well as Irish, Spanish and Italian. “One match is all we need, but it’s like a needle in a haystack.”

The Trujillos’ predicament highlights a nationwide paradox that has troubled medical experts and families awaiting transplants for years: despite the ever-growing diversity in the United States, there are not enough minority and multiracial donors registered and available for patients in need…

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In its focus on genetics and race, global newspaper coverage of athletics is far from “post-racial”

Posted in Articles, Communications/Media Studies, Health/Medicine/Genetics, Media Archive, Social Science on 2015-09-13 02:27Z by Steven

In its focus on genetics and race, global newspaper coverage of athletics is far from “post-racial”

The LSE’s daily blog on American Politics and Policy
The London School of Economics and Political Science
London, United Kingdom
2015-09-10

Matthew W. Hughey, Associate Professor of Sociology
University of Connecticut

Devon R. Goss, Ph.D. Candidate in Sociology
University of Connecticut

With the years of racially segregated sports now long behind us, many would consider that sports coverage is color-blind and post-racial. In new research which examines newspaper coverage of race, sport and genetics from 2003 to 2014, Matthew W. Hughey and Devon R. Goss find that this is not the case. They write that the media persistently reinforces the notions that African American’s athletic success is based on biology, while whites’ comes from hard work and intelligence. They also debunk the ideas often seen in the media that race has a biological reality which can be defined by genes, and that the historic process of slavery somehow eliminated ‘weaker genes’ from the African American population, making them a more athletic race.

For many, sport represents the ultimate color-blind space, affording a level playing field where only one’s training and skills are the hallmarks of competition. Hence, racist and prejudicial beliefs and phenomena are both literally and figuratively, out-of-bounds. Moreover, sport has been understood as an activity that promotes racial harmony amongst both participants and observers. But such a claim is a bit simplistic.

To make sense of the correlation between different racial groups’ success and failures amidst different athletic events, many draw from the deep well of scientific racism to quench their thirst for explanatory knowledge. For instance, some research has found that many athletes believe that white sporting success is attributable to intelligence, while nonwhite success is accredited to genetically predisposed bodies—a longstanding cultural trope known as “white brains versus black brawn”—that has been around for at least a century. After African American boxer Jack Johnson became the heavyweight champion of the world in 1908, he precipitated a slow reconsideration of the assumption of nonwhites’ physical inferiority—a central tenet of early 20th century racial science and eugenics. Fast forward to our contemporary moment and the banal ubiquity of this trope among sports commentators is well known, and was even recently panned by the comic duo Key & Peele

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Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Posted in Articles, Health/Medicine/Genetics, Media Archive, United States on 2015-09-09 19:35Z by Steven

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Genetics
August 1, 2015, Volume 200, Number 4
pages 1285-1295
DOI: 10.1534/genetics.115.178616

Yambazi Banda
Mark N. Kvale
Thomas J. Hoffmann
Stephanie E. Hesselson
Dilrini Ranatunga
Hua Tang
Chiara Sabatti
Lisa A. Croen
Brad P. Dispensa
Mary Henderson
Carlos Iribarren
Eric Jorgenson
Lawrence H. Kushi
Dana Ludwig
Diane Olberg
Charles P. Quesenberry Jr.
Sarah Rowell
Marianne Sadler
Lori C. Sakoda
Stanley Sciortino
Ling Shen
David Smethurst
Carol P. Somkin
Stephen K. Van Den Eeden
Lawrence Walter
Rachel A. Whitmer
Pui-Yan Kwok
Catherine Schaefer
Neil Risch

Using genome-wide genotypes, we characterized the genetic structure of 103,006 participants in the Kaiser Permanente Northern California multi-ethnic Genetic Epidemiology Research on Adult Health and Aging Cohort and analyzed the relationship to self-reported race/ethnicity. Participants endorsed any of 23 race/ethnicity/nationality categories, which were collapsed into seven major race/ethnicity groups. By self-report the cohort is 80.8% white and 19.2% minority; 93.8% endorsed a single race/ethnicity group, while 6.2% endorsed two or more. Principal component (PC) and admixture analyses were generally consistent with prior studies. Approximately 17% of subjects had genetic ancestry from more than one continent, and 12% were genetically admixed, considering only nonadjacent geographical origins. Self-reported whites were spread on a continuum along the first two PCs, indicating extensive mixing among European nationalities. Self-identified East Asian nationalities correlated with genetic clustering, consistent with extensive endogamy. Individuals of mixed East Asian–European genetic ancestry were easily identified; we also observed a modest amount of European genetic ancestry in individuals self-identified as Filipinos. Self-reported African Americans and Latinos showed extensive European and African genetic ancestry, and Native American genetic ancestry for the latter. Among 3741 genetically identified parent–child pairs, 93% were concordant for self-reported race/ethnicity; among 2018 genetically identified full-sib pairs, 96% were concordant; the lower rate for parent–child pairs was largely due to intermarriage. The parent–child pairs revealed a trend toward increasing exogamy over time; the presence in the cohort of individuals endorsing multiple race/ethnicity categories creates interesting challenges and future opportunities for genetic epidemiologic studies.

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Suit filed over mix-up at Downers Grove sperm bank is dismissed

Posted in Articles, Health/Medicine/Genetics, Law, Media Archive, United States on 2015-09-07 01:21Z by Steven

Suit filed over mix-up at Downers Grove sperm bank is dismissed

The Chicago Tribune
2015-09-03

Clifford Ward

A judge Thursday dismissed a lawsuit filed by an Ohio woman against a west suburban sperm bank whose clerical error resulted in the birth of her mixed-race daughter.

DuPage County Judge Ronald Sutter tossed the suit after lawyers for Midwest Sperm Bank argued that the woman’s claims lacked legal merit. But the judge said Jennifer Cramblett of Uniontown, Ohio, could refile her lawsuit under a negligence claim.

Cramblett, who did not attend Thursday’s hearing, filed suit last year against the Downers Grove-based sperm bank alleging wrongful birth and breach of warranty following the birth of her daughter, who is of African-American ancestry.

Cramblett and her same-sex partner purchased sperm with the understanding that it was from a Caucasian donor, but later discovered that the sperm bank had sent material from an African-American donor. The mistake was caused by a clerical error, and the bank later issued an apology and a partial refund…

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Inconsistency within Expressed and Observed Racial Identifications: Implications for Mental Health Status

Posted in Articles, Health/Medicine/Genetics, Identity Development/Psychology, Media Archive, Social Science, United States on 2015-08-30 02:32Z by Steven

Inconsistency within Expressed and Observed Racial Identifications: Implications for Mental Health Status

Sociological Perspectives
Published online before print 2015-08-29
DOI: 10.1177/0731121415602133

Whitney N. Laster Pirtle, Assistant Professor of Sociology
University of California, Merced

Tony N. Brown, Associate Professor of Sociology
Vanderbilt University, Nashville, Tennessee

The present study extends previous work on distress that arises from discrepancy between self and interviewer racial identifications. Using the National Longitudinal Study of Adolescent to Adult Health (Add Health) data, we examine mental health consequences of inconsistency over time within expressed (self) and observed (interviewer) racial identifications among American Indians. Given that phenotype signals race, we also contribute to prior research by examining whether skin color moderates inconsistency’s mental health consequences. Analyses show that observed racial inconsistency increased American Indians’ depressive symptoms and suicidal ideation. That is, when interviewers labeled a respondent “American Indian” at one wave of data but not another, there were deleterious implications for mental health status. In addition, an interaction between observed inconsistency and skin color demonstrated that observed inconsistency tended to be harmful when respondents were observed as having light skin. We argue observed inconsistency captures the distressing experience of being not readily classifiable.

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Photographer Explores The Beautiful Diversity Of Redheads Of Color

Posted in Articles, Arts, Health/Medicine/Genetics, Media Archive on 2015-08-25 17:45Z by Steven

Photographer Explores The Beautiful Diversity Of Redheads Of Color

The Huffington Post
2015-08-25

Priscilla Frank, Arts Writer


Michelle Marshall

Red hair is usually the result of a mutation in a gene called MC1R, also known as a melanocortin 1 receptor. Normally, when activated by a certain hormone, MC1R sparks a series of signals that leads to the production of brown or black pigment. Yet, in cases when both parents are carriers of the recessive MC1R gene and said receptor is mutated or antagonized, it fails to turn hair darker, resulting instead in a beautifully fiery buildup of red pigment.

As previously estimated by BBC News, between one and two percent of the world’s population — or 70 to 140 million people — are redheads. In Scotland and Ireland, around 35 percent of the population carry the recessive gene that yields crimson locks, and the redhead count is around 10 percent. As such, the word ginger often calls to mind visions of Celtic-Germanic attributes — namely, pale, white skin…

White skin and red hair may constitute the stereotypical image of a redhead, but it’s by no means a comprehensive one. French-born, London-based photographer Michelle Marshall is documenting the stunningly diverse manifestations of the MC1R gene, particularly in people of color…

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Mixed-race heritage complicates stem cell search

Posted in Articles, Canada, Health/Medicine/Genetics, Media Archive on 2015-08-25 01:23Z by Steven

Mixed-race heritage complicates stem cell search

Radio Canada International
2015-08-24

Lynn Desjardins

A 19-year-old woman with cancer is having trouble finding a stem cell donor because of her mixed aboriginal and Irish roots. Rosalie Lirette Gilbert was diagnosed on June 29 with acute lymphoblastic leukemia—a cancer of the blood and bone marrow….

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How beliefs in biological differences can undergird racial and policy attitudes

Posted in Articles, Health/Medicine/Genetics, Media Archive, Politics/Public Policy on 2015-08-25 01:10Z by Steven

How beliefs in biological differences can undergird racial and policy attitudes

The London School of Economics and Political Science
2015-08-24

W. Carson Byrd, Assistant Professor of Pan-African Studies
University of Louisville, Louisville, Kentucky

Beliefs in biological differences between racial groups linger in both scientific and public discourse. Recent advances in genetics and genomics influence public understandings of racial inequality. In a recent study examining whites’ views of race, genetics, and public policies in the U.S., Carson Byrd finds that beliefs in biological differences between racial groups can influence people’s support for policies aimed at reducing racial inequalities, and uncovers the complexities of how people conceptualize and utilize race to understand everyday life.

It has been 15 years since then President Bill Clinton and leading scientists of the Human Genome Project made their highly-acclaimed proclamations that race at the genetic level does not exist. At the time this supported the long-held narrative of scholars that the once prominent beliefs in biological determinism (race as a genetic reality) and racial essentialism (human behavior is anchored in group-based biological differences) had been all but completely laid to rest in the archives of history, particularly after the fall of the Nazi regime and the end of the Holocaust after World War II. However, these beliefs in race and genetics may be making a comeback as genetic and genomic research gains in popularity and media visibility. As sociologist Lawrence Bobo and colleagues recently note in their analysis of survey data, there is a recent uptick the last decade in the belief that there are innate (i.e., biological or genetic) racial differences that drive racial inequality…

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Biological Determinism and Racial Essentialism

Posted in Articles, Health/Medicine/Genetics, Law, Media Archive, Social Science, United States on 2015-08-24 02:14Z by Steven

Biological Determinism and Racial Essentialism

The ANNALS of the American Academy of Political and Social Science
Volume 661, Number 1, September 2015
pages 8-22
DOI: 10.1177/0002716215591476

W. Carson Byrd, Assistant Professor of Pan-African Studies
University of Louisville, Louisville, Kentucky

Matthew W. Hughey, Professor of Sociology
University of Connecticut

In August 2012, nine months after being artificially inseminated using a sperm donation from the Midwest Sperm Bank of Downers Grove, Illinois, a white Ohio woman named Jennifer Cramblett gave birth to a racially “mixed” and healthy baby girl named Payton. Despite the triumph, the woman soon filed a “wrongful birth” suit in Cook County Circuit Court, alleging that the sperm bank gave her sperm vials from an African American donor instead of a white donor, which in turn caused “personal injuries . . . pain, suffering, emotional distress and other economic and non-economic losses” (Circuit Court 2014, 8). The lawsuit states “that they now live each day with fears, anxieties and uncertainty about her future and Payton’s future” (Circuit Court 2014, 6).

The supposed racial mismatch between parent and child in Cramblett v. Midwest Sperm Bank reveals the presence of two powerful belief systems that haunt both the popular imagination and stalk the scientific landscape: the notions of “biological determinism” (that race is genetically inherited) and “racial essentialism” (that group-based biology maps to basic social behaviors). Together, biological determinism and racial essentialism form the “ideological double helix” that intertwines to shape beliefs about race and inequality and influence the theoretical approaches, analytic strategies, and interpretations taken by scholars conducting biomedical and social scientific research. The suit turns on the assumption that varied racial groups have bounded and characteristically unique arrangements of genetic material: as the complaint contends, “Their desire was to find a donor with genetic traits similar to both of them” (Circuit Court 2014, 2–3). Such devotion to racial essentialism motivates a belief that the two white parents in this case are more similar to each other (because of their shared “whiteness”) than they are to their child (because of an unknown “black” father), even though the…

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The Risks of Turning Races Into Genes

Posted in Articles, Health/Medicine/Genetics, Media Archive, Politics/Public Policy, Social Science on 2015-08-24 01:25Z by Steven

The Risks of Turning Races Into Genes

The Huffington Post
2015-08-20

Matthew W. Hughey, Professor of Sociology
University of Connecticut

From 22-25 August, sociologists from around the nation and world will descend upon the Windy City of Chicago to discuss sundry issues as they participate in the annual meeting of the American Sociological Association. One issue, however, is quite controversial: do genes or the social environment determine our behavior and health? Precisely, does nature or nurture determine the outcome of racial differences and racial inequality found throughout society?

Many readily acknowledge scientific advances are a necessary part of an improving society. From making cars more efficient on the road and beaming pictures from Pluto across the solar system to Earth, to developing new medical procedures to help us live better and making a longer lasting light bulb. Despite the many improvements science affords, cultural bias and normative assumptions can undergird the scientific methods and lead us down a dangerous path that has plagued American society for centuries. This path relies on a logic about race and difference that was and continues to be shared by many: from Thomas Jefferson to Dylan Roof, the white supremacist who murdered nine African American churchgoers in Charleston this summer. What may be even more surprising is that a variation of this same logic can infiltrate science and influences how we understand who achieves better jobs and even who succeeds at professional sports.

In the just released issue of The ANNALS of the American Academy of Political and Social Science we edited, I have gathered (with Professor W. Carson Byrd) an array of experts on race, science, technology, and society to explain how the fiction of “race” can have very real consequences. By exploring both biological determinism and racial essentialism together–what I and Professor Byrd call the “ideological double helix”–we explain how misunderstandings of race, genes, and inequality frequently creep into supposedly an objective science…

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