Racial Prescriptions: Pharmaceuticals, Difference, and the Politics of Life

Posted in Books, Health/Medicine/Genetics, Media Archive, Monographs, Politics/Public Policy on 2015-05-10 17:09Z by Steven

Racial Prescriptions: Pharmaceuticals, Difference, and the Politics of Life

Ashgate
September 2014
148 pages
234 x 156 mm
Hardback ISBN: 978-1-4094-4498-5
eBook PDF ISBN: 978-1-4094-4499-2
eBook ePUB ISBN: 978-1-4724-0107-6

Jonathan Xavier Inda, Associate Professor of Latina/Latino Studies
University of Illinois, Urbana-Champaign

In the contemporary United States, matters of life and health have become key political concerns. Important to this politics of life is the desire to overcome racial inequalities in health; from heart disease to diabetes, the populations most afflicted by a range of illnesses are racialized minorities. The solutions generally proposed to the problem of racial health disparities have been social and environmental in nature, but in the wake of the mapping of the human genome, genetic thinking has come to have considerable influence on how such inequalities are problematized. Racial Prescriptions explores the politics of dealing with health inequities through targeting pharmaceuticals at specific racial groups based on the idea that they are genetically different. Drawing on the introduction of BiDil to treat heart failure among African Americans, this book contends that while racialized pharmaceuticals are ostensibly about fostering life, they also raise thorny questions concerning the biologization of race, the reproduction of inequality, and the economic exploitation of the racial body.

Engaging the concept of biopower in an examination of race, genetics and pharmaceuticals, Racial Prescriptions will appeal to sociologists, anthropologists and scholars of science and technology studies with interests in medicine, health, bioscience, inequality and racial politics.

Contents

  • Acknowledgments
  • 1. Racial politics of life
  • 2. The making of BiDil
  • 3. Biosocial citizenship
  • 4. Enlightened geneticization of race
  • 5. Racial vital value
  • 6. Neoliberalization of life
  • Bibliography
  • Index
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UCLA researchers say Japanese-Americans’ healthier golden years could be a model for other seniors

Posted in Articles, Asian Diaspora, Health/Medicine/Genetics, Media Archive, United States on 2015-05-05 17:42Z by Steven

UCLA researchers say Japanese-Americans’ healthier golden years could be a model for other seniors

UCLA Newsroom
University of California, Los Angeles
2015-04-29

Venetia Lai

Nearly 1 in 4 Japanese-Americans are 65 and older — nearly twice the proportion of seniors in the overall U.S. population. The facts that they are likelier to live longer than other Americans and are healthier when they age make Japanese-Americans an important subject of research by health policy experts — and could provide clues about how all Americans can age, according to a new study by the UCLA Center for Health Policy Research.

Using California Health Interview Survey data from 2003 to 2012, the study found that elderly Japanese-Americans had lower risks for nine of 15 health indicators than other Asian and other racial and ethnic groups in California. Older Japanese-Americans, however, did have higher rates of arthritis and hypertension than seniors in other racial and ethnic groups.

“Japanese-Americans provide a window into our future,” said Ying-Ying Meng, lead author of the study and co-director of the center’s Chronic Disease Program. “They show us one vision of how our nation can age and can help us prepare for the enormous generational shift ahead.”

The report, which was funded by Keiro Senior HealthCare, examines three categories of Japanese in California: Those who identify as being “only” Japanese — typically with parents who both were Japanese; those who identify as being mixed-race; and those who identified as being Japanese in some way…

Read the entire article here.

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Ancient DNA Tells a New Human Story

Posted in Articles, Health/Medicine/Genetics, Media Archive on 2015-05-04 18:08Z by Steven

Ancient DNA Tells a New Human Story

The Wall Street Journal
2015-05-01

Matt Ridley

Armed with old bones and new DNA sequencing technology, scientists are getting a much better understanding of the prehistory of the human species, writes Matt Ridley

Imagine what it must have been like to look through the first telescopes or the first microscopes, or to see the bottom of the sea as clearly as if the water were gin. This is how students of human prehistory are starting to feel, thanks to a new ability to study ancient DNA extracted from bodies and bones in archaeological sites.

Low-cost, high-throughput DNA sequencing—a technique in which millions of DNA base-pairs are automatically read in parallel—appeared on the scene less than a decade ago. It has already transformed our ability to see just how the genes of human beings, their domestic animals and their diseases have changed over thousands or tens of thousands of years.

The result is a crop of new insights into precisely what happened to our ancestors: when and where they migrated, how much they intermarried with those they met along the way and how their natures changed as a result of evolutionary pressures. DNA from living people has already shed some light on these questions. Ancient DNA has now dramatically deepened—and sometimes contradicted—those answers, providing a much more dynamic view of the past.

It turns out that, in the prehistory of our species, almost all of us were invaders and usurpers and miscegenators. This scientific revelation is interesting in its own right, but it may have the added benefit of encouraging people today to worry a bit less about cultural change, racial mixing and immigration.

Consider two startling examples of how ancient DNA has solved long-standing scientific enigmas. Tuberculosis in the Americas today is derived from a genetic strain of the disease brought by European settlers. That is no great surprise. But there’s a twist: 1,000-year-old mummies found in Peru show symptoms of TB as well. How can this be—500 years before any Europeans set foot in the Americas?…

Read the entire article here.

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Genes Don’t Cause Racial-Health Disparities, Society Does

Posted in Articles, Health/Medicine/Genetics, Media Archive, United States on 2015-04-27 19:24Z by Steven

Genes Don’t Cause Racial-Health Disparities, Society Does

The Atlantic
2015-04-13

Jason Silverstein, Teaching Fellow in Anthropology
Harvard University

Researchers are looking in the wrong place: White people live longer not because of their DNA but because of inequality.

On April 24, 2003, shortly after the completion of the human genome project, its director Francis Collins and his team posed 15 grand challenges to the scientific community. They dared researchers to harness the genome to crack puzzles of biology, health, and society. In particular, they called for genome-based tools to close health disparities. Since then, the United States has pumped more than $1 billion a year into genomics research. What do we have to show for it?

“What we found in the literature published from 2007 to 2013 was basically nothing,” said Jay Kaufman, the lead author of the first study to examine available genetic data for evidence that explains a major racial-health disparity. For many years, researchers speculated that what they couldn’t explain about disparities must be the fingerprint of some mysterious genetic component. But since they are now able to scan the entire genome, this speculation appears both lazy and wrong. When it comes to why many black people die earlier than white people in the U.S., Kaufman and his colleagues show we’ve been looking for answers in the wrong places: We shouldn’t be looking in the twists of the double helix, but the grinding inequality of the environment.

It is no secret that a longer life is a white privilege in the U.S. In 2011, the Centers for Disease Control and Prevention (CDC) reported that white men lived more than four years longer than black men, and white women lived more than three years longer than black women. The main reason for the racial mortality gap is heart disease. “There’s a huge number of years of life lost because some people have the black life expectancy and not the white life expectancy,” Kaufman said. “It’s killing people prematurely on the basis of race.”…

Read the entire article here.

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Breast cancer and racialized medicine

Posted in Articles, Health/Medicine/Genetics, Media Archive, United States on 2015-04-16 22:17Z by Steven

Breast cancer and racialized medicine

Race, Racism & Human Genetics IDS 243: Race, Racism, and Human Genetics
Willamette University
Salem, Oregon
2014-11-28

Stephanie Matsuura

Katie Herr

Camille Debreczeny

Race, Racism & Human Genetics IDS 243: Race, Racism, and Human Genetics is an interdisciplinary course taught at Willamette University by Emily Drew and Chris Smith. This blog represents the work of students enrolled in the course, and their reactions to current scholarly and popular work relating to the biology of human difference.

Racial disparities in breast cancer are often attributed to biology uncritically, without considering social factors. In many genetic studies, rhetorical framing of human diversity conflates differences between populations with racial categories. An unconscious complicity in the racial worldview informs these studies, which are then used to justify racialized explanations for disparities in breast cancer. Many researchers recognize that individualized, complete genome analysis would provide better care for patients, but lack the technological and economic resources to make this a realistic goal. Instead they rely on racialized medicine, which has serious consequences for women of color with breast cancer.

Racialized medicine occurs when the U.S. racial worldview goes unchallenged in the way it shapes medical research, health care practices, and public health policy. It is a way of making inequalities in health and illness seem natural by erroneously linking them to “innate” and “biological” differences between racial groups. In the U.S., women of color are disproportionately affected by breast cancer. Black women in particular have higher breast cancer mortality rates than any other racial/ethnic group in the country (Happe 2006). In this blog we aim to cover the main possible explanations for observed racial disparities in both incidence and prognosis of breast cancer. Studies have attributed racial disparities in both incidence and prognosis to the genetics underlying breast cancer as well as to social factors…

Read the entire article here.

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IDS 243 Race, Racism, & Human Genetics

Posted in Course Offerings, Health/Medicine/Genetics, Media Archive, Social Science, United States on 2015-04-16 21:15Z by Steven

IDS 243 Race, Racism, & Human Genetics

Willamette University
Salem, Oregon
Fall 2014

What accounts for human difference, and what does the biology of human variation tell us about race and the “life changes” of racial groups in contemporary society? This course examines the relationship between genes, geography, skin color and what we have come to understand as “race.” It will focus upon patterns of human genetic variation and consider how the completion of the Human Genome Project and the increasing availability of genomic data have changes our understanding of human population genetics. It will also address the historical role of science in taking the socially-constructed concept of race and turning it into scientific “fact,” and explore how this past history both shapes and constrains contemporary research in the biology of human diversity. The course will consider contemporary case studies in which race becomes—and is ascribed to—biology in ways that both reflect and contribute to dominant racial ideology. By bringing together the research about race from the natural and social sciences, the course seeks to understand how biological and social factors interact to shape racial reality and explores the political and social implications for scientific inquiry.

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How Europeans evolved white skin

Posted in Articles, Europe, Health/Medicine/Genetics, Media Archive on 2015-04-06 01:26Z by Steven

How Europeans evolved white skin

Science
2015-04-02
DOI: 10.1126/science.aab2435

Ann Gibbons, Contributing Correspondent

ST. LOUIS, MISSOURI—Most of us think of Europe as the ancestral home of white people. But a new study shows that pale skin, as well as other traits such as tallness and the ability to digest milk as adults, arrived in most of the continent relatively recently. The work, presented here last week at the 84th annual meeting of the American Association of Physical Anthropologists, offers dramatic evidence of recent evolution in Europe and shows that most modern Europeans don’t look much like those of 8000 years ago.

The origins of Europeans have come into sharp focus in the past year as researchers have sequenced the genomes of ancient populations, rather than only a few individuals. By comparing key parts of the DNA across the genomes of 83 ancient individuals from archaeological sites throughout Europe, the international team of researchers reported earlier this year that Europeans today are a mix of the blending of at least three ancient populations of hunter-gatherers and farmers who moved into Europe in separate migrations over the past 8000 years. The study revealed that a massive migration of Yamnaya herders from the steppes north of the Black Sea may have brought Indo-European languages to Europe about 4500 years ago.

Now, a new study from the same team drills down further into that remarkable data to search for genes that were under strong natural selection—including traits so favorable that they spread rapidly throughout Europe in the past 8000 years. By comparing the ancient European genomes with those of recent ones from the 1000 Genomes Project, population geneticist Iain Mathieson, a postdoc in the Harvard University lab of population geneticist David Reich, found five genes associated with changes in diet and skin pigmentation that underwent strong natural selection…

Read the entire article here.

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Breathing Race into the Machine: The Surprising Career of the Spirometer from Plantation to Genetics by Lundy Braun (review)

Posted in Articles, Book/Video Reviews, Health/Medicine/Genetics, History, Media Archive, United Kingdom, United States on 2015-04-03 19:37Z by Steven

Breathing Race into the Machine: The Surprising Career of the Spirometer from Plantation to Genetics by Lundy Braun (review)

Configurations
Volume 23, Number 1, Winter 2015
pages 127-130
DOI: 10.1353/con.2015.0000

Lindsey Andrews, Visiting Scholar of English
Center for Interdisciplinary Studies in Science and Cultural Theory
Duke University, Durham, North Carolina

Braun, Lundy, Breathing Race into the Machine: The Surprising Career of the Spirometer from Plantation to Genetics (Minneapolis: University of Minnesota Press, 2014).

Lundy Braun’s account of the ongoing and often invisible implementation of race-correction in pulmonary medicine is as much about the absence of the spirometer—a machine developed to measure lung function with accuracy—as it is about its presence. Breathing Race into the Machine: The Surprising Career of the Spirometer from Plantation to Genetics asks how it is possible that, well into the twenty-first century, doctors continue to use technologies that “correct” for racial differences in lung function despite no existing physiological difference. How did buttons establishing separate norms based on race and sex come to be a surreptitious, yet pervasive feature of diagnostic machinery? The answer lies in a much larger story about the desirability, across multiple domains and professions, of a technically precise means for measuring the elusive quality that physicians, scientists, and insurance companies came to think of as “vital capacity” or “fitness.” Building explicitly on Keith Wailoo’s Drawing Blood: Technology and Disease Identity in Twentieth-Century America (1997) and contributing to a growing body of literature on race in science and technology, Braun’s study “examine[s] the complex and contradictory historical processes by which differences such as race, class, and gender actually get embedded into the very architecture of scientific instruments” (p. xxi).

Braun tracks the proliferation of spirometric uses, from the machine’s earliest emergence as a tool for monitoring laborers’ fitness in the middle of the nineteenth century, through its development as a medical diagnostic tool in the twentieth century, to its contemporary role in adjudicating worker’s compensation claims. One of the most intriguing aspects of Braun’s book—and at times its most challenging feature—is its attempt to account for the ways in which the spirometer’s flexibility (rather than its specificity) as a precision tool and its unclear object of measurement (vital capacity) made it, in fact, such a powerful tool that would come to play a crucial global role in health- and insurance-policy decisions. What Braun ultimately shows is that separate though related epistemological problems regarding vital capacity emerged across multiple fields—including labor surveillance, fitness culture, and diagnostic medicine—to which precision and numeracy appeared to be the answer. The spirometer provided both. As Braun notes, spirometry was not central to any one discipline, but instead found myriad uses in physical education, military testing and training, and insurance assessment. “As its epistemological relevance faded in one domain,” she writes, “it was taken up, adapted, and investigated in another” (p. xxv). Whether shoring up Anglo-Saxon masculinity by establishing the superiority of upper-class white lungs in nineteenth-century physical culture or enforcing anti-black workers’ compensation policies that required blacks to demonstrate even lower lung functioning than similarly positioned white workers in order to receive remuneration, the capacity of the spirometer to produce numeric data was both its appeal in terms of authority and simultaneously its most easily racialized feature—a feature made invisible in the apparent “value neutrality” of a scientific virtue (a concept that Braun draws from Lorainne Daston and Peter Galison) like precision.

Tracing the international and professional border-crossing of the spirometer is one of the book’s primary accomplishments, but also one of its challenges for readers. In the course of seven chapters, Braun is tasked with moving back and forth from the twenty-first to the early nineteenth century, and from Wales, to the US South, to South Africa, negotiating a narrative that is neither straightforward nor linear, although always following a through-line in which assessment of the laboring body and management of the laboring class drive spirometric racialization. Early chapters cover the stabilization of whiteness as a meaning of lung-capacity measurements. In the first chapter, Braun shows how John Hutchinson, a Victorian scientist and early developer of the spirometer, reconfigured pulmonary studies in terms of physiological functioning rather than anatomical construction, thus tapping into growing investments in scientific experimentalism and the “quantifying spirit” of the Victorian era by adapting the spirometer’s use to large-scale population studies. Chapter 1 thus lays the groundwork for the third and fourth chapters, which also detail the ways in which lung-capacity measurements, along with anthropometry

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“General Heads,” Great Minds, and the Genesis of Scientific Racism

Posted in Anthropology, Articles, Health/Medicine/Genetics, History, Media Archive on 2015-03-23 01:02Z by Steven

“General Heads,” Great Minds, and the Genesis of Scientific Racism

Journal for Early Modern Cultural Studies
Volume 15, Number 2, Spring 2015
pages 112-118

Robin Runia, Assistant Professor of English
Xavier University of Louisiana, New Orleans, Louisiana

It is commonly presum’d that the Heat of the Climate wherein they live, is the reason, why so many Inhabitants of the Scorching Regions of Africa are Black; and there is this familiar Observation to Countenance this Conjecture, That we plainly see that Mowers, Reapers, and other Countrey-people, who spend the most part of the Hot Summer dayes expos’d to the Sun, have the skin of their Hands and Faces, which are the parts immediately Expos’d to the Sun and Air, made of a Darker Colour than before, and consequently tending to Blackness; And Contrarywise we observe that the Danes and some other people that Inhabit Cold Climates, and even the English who feel not so Rigorous a Cold, have usually Whiter faces than the Spaniards, Portugalls and other European Inhabitants of Hotter Climates. But this Argument I take to be far more Specious than Convincing. (153–54)

There is another Opinion concerning the Complexion of Negroes, that . . . the Blackness of Negroes [is] an effect of Noah’s Curse ratify’d by God’s, upon Cham; But though I think that even a Naturalist may without disparagement believe all the Miracles attested by the Holy Scriptures, yet in this case to flye to a Supernatural Cause, will, I fear, look like Shifting off the Difficulty, instead of Resolving it; for we enquire not the First and Universal, but the Proper, Immediate, and Physical Cause of the Jetty Colour of Negroes; And not only we do not find expressed in the Scripture, that the Curse meant by Noah to Cham, was the Blackness of his Posterity, but we do find plainly enough there that the Curse was quite another thing, namely that he should be a Servant of Servants, that is by an Ebraism, a very Abject Servant to his Brethren. . . . Nor is it evident that Blackness is a Curse, for Navigators tell us of Black Nations, who think so much otherwise of their own condition, that they paint the Devil White. Nor is Blackness inconsistent with Beauty, which even to our European Eyes consists not so much in Colour, as an Advantageous Stature, a Comely Symmetry of the parts of the Body, and Good Features in the Face. So that I see not why Blackness should be thought such a Curse to the Negroes, unless perhaps it be, that being wont to go Naked in those Hot Climates, the Colour of their Skin does probably, according to the Doctrine above deliver’d, make the Sunbeams more Scorching to them, than they would prove to a people of a White Complexion. (159–60)

Greater probability there is, That the Principal Cause (for I would not exclude all concurrent ones) of the Blackness of Negroes is some Peculiar and Seminal Impression. (161)

—Robert Boyle, Experiments and Considerations Touching Colours (1664)

The above extracts present Robert Boyle’s delineation of racialized difference, as produced and evaluated by the Royal Society; this delineation, production, and evaluation is the lifeblood of Cristina Malcolmson’s Studies of Skin Color in the Royal Society. Exploring the development of the modern notion of race within the context of colonialism, Malcolmson argues that “the attention to skin color in the Royal Society allowed racialization to develop and eventually flourish within the practices of the new science” (7). Specifically, attention to the imbrication of this process within institutional and economic commitments to British imperial dominance helps to fill in the gaps between an attention to skin color, consideration of its causes, and the dehumanization and subjugation of non-European individuals. Malcolmson’s focus on the Royal Society’s activities and publications and on Margaret Cavendish’s and Jonathan Swift’s reactions to them provides an important and nuanced contribution to the recent scholarship in this area as well as a call for additional work to be done.

The value of this volume lies in Malcolmson’s thorough presentation of compelling evidence and insightful close readings that expose the Royal Society’s complicity in the spread of racialized discourse and racist thought. In addition, Malcomson’s original contributions to scholarship on the historical construction of race include her critique of polygenesis as inherently racist and her methodical…

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Genetics: No evidence of role in racial mortality gap

Posted in Articles, Health/Medicine/Genetics, Media Archive on 2015-03-20 00:48Z by Steven

Genetics: No evidence of role in racial mortality gap

Science Daily: Your source for the latest research news
2015-03-16

There is still no evidence of genetic difference between blacks and whites to account for the health disparities in cardiovascular disease (CVD), according to a new study by McGill University researchers. Published in the American Journal of Epidemiology, the researchers suggest that after a decade of genetic studies, factors such as lifestyle, education and socio-economics — not genetics — are more promising avenues to understanding racial health disparities.

The researchers focused on cardiovascular disease, the largest contributor to the racial mortality gap, and conducted a systematic review for articles published over a seven year period in which genetic data from African and European populations were available. The team found no explanation for racial disease disparities amongst any of the hundreds of genetic variants reported.

“After nearly a decade of genome-wide association studies (GWAS), no assessment had yet been made of their contribution toward an explanation of the most prominent racial health disparities observed at the population level,” says Jay Kaufman, of the Department of Epidemiology, Biostatistics & Occupational Health in the Faculty of Medicine…

Read the entire article here.

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