‘Race Unmasked’ explores science’s racial past, present

Posted in Articles, Book/Video Reviews, Health/Medicine/Genetics, Media Archive on 2014-12-29 02:41Z by Steven

‘Race Unmasked’ explores science’s racial past, present

Science News: Magazine of the Society for Science & The Public
2014-11-30
Magazine Issue: Volume 186, Number 12, December 13, 2014

Bryan Bello, Editorial Assistant

Race Unmasked: Biology and Race in the 20th Century. Michael Yudell. Columbia University Press, $40

It’s 1921 and the American Museum of Natural History in New York City is packed with visitors eager to learn about the hot science of eugenics. AMNH staff dubs its conference and exhibit “the most important scientific meeting ever held in the museum.” In his new book, Yudell, a historian of public health, argues that the complicated interaction of science and race visible in the eugenics movement is still playing out. “Thinking in the natural sciences has influenced the continued evolution of racist ideology in the United States,” he writes.

An inversion also holds true: Racist ideology has shaped — and continues to sway — the evolution of science. The result is a constant trade-off of influence between popular culture and science.

Yudell dissects key moments in innovation. For example, Mendelian genetics arose and was appropriated by eugenicists to falsely link complex personal attributes to heredity.  In addition, by midcentury, leading anthropologists accepted Africa as the birthplace of the genus Homo, but then several researchers spun off theories positing that different races are Homo sapiens subspecies…

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White? Black? A Murky Distinction Grows Still Murkier

Posted in Anthropology, Articles, Health/Medicine/Genetics, History, Latino Studies, Law, Media Archive, Native Americans/First Nation, Slavery, United States on 2014-12-24 17:50Z by Steven

White? Black? A Murky Distinction Grows Still Murkier

The New York Times
2014-12-24

Carl Zimmer

In 1924, the State of Virginia attempted to define what it means to be white.

The state’s Racial Integrity Act, which barred marriages between whites and people of other races, defined whites as people “whose blood is entirely white, having no known, demonstrable or ascertainable admixture of the blood of another race.”

There was just one problem. As originally written, the law would have classified many of Virginia’s most prominent families as not white, because they claimed to be descended from Pocahontas.

So the Virginia legislature revised the act, establishing what came to be known as the “Pocahontas exception.” Virginians could be up to one-sixteenth Native American and still be white in the eyes of the law.

People who were one-sixteenth black, on the other hand, were still black.

In the United States, there is a long tradition of trying to draw sharp lines between ethnic groups, but our ancestry is a fluid and complex matter. In recent years geneticists have been uncovering new evidence about our shared heritage, and last week a team of scientists published the biggest genetic profile of the United States to date, based on a study of 160,000 people…

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Do Races Differ? Not Really, Genes Show

Posted in Articles, Health/Medicine/Genetics, Media Archive on 2014-12-23 19:55Z by Steven

Do Races Differ? Not Really, Genes Show

The New York Times
2000-08-22

Natalie Angier, Science Columnist

In these glossy, lightweight days of an election year, it seems, they can’t build metaphorical tents big or fast enough for every politician who wants to pitch one up and invite the multicultural folds to ”Come on under!” The feel-good message that both parties seek to convey is: regardless of race or creed, we really ARE all kin beneath the skin.

Yet whatever the calculated quality of this new politics of inclusion, its sentiment accords firmly with scientists’ growing knowledge of the profound genetic fraternity that binds together human beings of the most seemingly disparate origins.

Scientists have long suspected that the racial categories recognized by society are not reflected on the genetic level. But the more closely that researchers examine the human genome — the complement of genetic material encased in the heart of almost every cell of the body — the more most of them are convinced that the standard labels used to distinguish people by ”race” have little or no biological meaning.

They say that while it may seem easy to tell at a glance whether a person is Caucasian, African or Asian, the ease dissolves when one probes beneath surface characteristics and scans the genome for DNA hallmarks of “race.”…

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The uncanny return of the race concept

Posted in Articles, Health/Medicine/Genetics, Identity Development/Psychology, Media Archive, Social Science on 2014-12-23 15:35Z by Steven

The uncanny return of the race concept

Frontiers in Human Neuroscience
Volume 8, 2014-11-04
DOI: 10.3389/fnhum.2014.00836

Andreas Heinz
Department of Psychiatry and Psychotherapy
Charité—University Medicine Berlin, Berlin, Germany

Daniel J. Müller, Associate Professor of Psychiatry
Centre for Addiction and Mental Health
Department of Psychiatry
University of Toronto, Toronto, Ontario, Canada

Sören Krach
Department of Child and Adolescent Psychiatry
Philipps-University Marburg, Marburg, Germany

Maurice Cabanis
Center for Mental Health, Klinikum Stuttgart, Stuttgart, Germany

Ulrike P. Kluge
Department of Psychiatry and Psychotherapy
Charité—University Medicine Berlin, Berlin, Germany

The aim of this Hypothesis and Theory is to question the recently increasing use of the “race” concept in contemporary genetic, psychiatric, neuroscience as well as social studies. We discuss “race” and related terms used to assign individuals to distinct groups and caution that also concepts such as “ethnicity” or “culture” unduly neglect diversity. We suggest that one factor contributing to the dangerous nature of the “race” concept is that it is based on a mixture of traditional stereotypes about “physiognomy”, which are deeply imbued by colonial traditions. Furthermore, the social impact of “race classifications” will be critically reflected. We then examine current ways to apply the term “culture” and caution that while originally derived from a fundamentally different background, “culture” is all too often used as a proxy for “race”, particularly when referring to the population of a certain national state or wider region. When used in such contexts, suggesting that all inhabitants of a geographical or political unit belong to a certain “culture” tends to ignore diversity and to suggest a homogeneity, which consciously or unconsciously appears to extend into the realm of biological similarities and differences. Finally, we discuss alternative approaches and their respective relevance to biological and cultural studies.

TABLE OF CONTENTS

  • Abstract
  • Introduction
  • The Origin of the “Race Concept” and Controversies about its Biological Usefulness
  • Cultural Impact on Race Classifications
  • Racial Classifications, Colonial Hierarchies and the Construction of the Psychotic Patient as Primitive Man
  • The Social Impact of “Race” Classifications
  • “Culture” as a Proxy of “Race”
  • Implications of Cultural and Genetic Diversity in Psychiatry
  • Summary and Outlook
  • Conflict of Interest Statement
  • Acknowledgments
  • References

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Black And White In America: Study Reveals Many Americans Have Mixed Race Background They Were Unaware Of

Posted in Articles, Health/Medicine/Genetics, Media Archive, United States on 2014-12-19 21:40Z by Steven

Black And White In America: Study Reveals Many Americans Have Mixed Race Background They Were Unaware Of

Medical Daily
New York, New York
2014-12-18

Dana Dovey, Health Journalist

Earlier this year, National Geographic made headlines with its “Changing Face of America” article. The story explained that America was becoming more comfortable with interracial relationships, and as a result, the future would be made up of a group of people with features from multiple races. A new study has challenged this hypothesis and suggested that this “mixed race future” is already here. We just never realized it.

The study, published by Cell Press, found that there is quite a large difference in the race that people identify with and what they actually are. In a recent study, researchers analyzed the DNA of more than 160,000 Americans who had offered their saliva as part of the 23andMe project. What researchers found was surprising.

The study found that, as expected, people tended to identify with the race that made up the majority of their background. However, for many, this self-identification was not completely accurate. According to the press release, the team estimated that as many as six million Americans who identify as white from a European background carry African ancestry and as many as five million self-described European white Americans have Native American ancestry….

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The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States

Posted in Articles, Health/Medicine/Genetics, Latino Studies, Media Archive, Native Americans/First Nation, United States on 2014-12-19 02:12Z by Steven

The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States

The American Journal of Human Genetics
Volume 96, Issue 1, 2015-01-08
Pages 37–53
DOI: 10.1016/j.ajhg.2014.11.010

Katarzyna Bryc, Research Fellow in Genetics (EXT)
Department of Genetics
Harvard Medical School, Boston, Massachusetts

Eric Y. Durand
23andMe, Inc., Mountain View, California

J. Michael Macpherson, Assistant Professor
School of Computational Sciences
Chapman University, Orange, California

David Reich, Professor of Genetics
Harvard Medical School, Boston, Massachusetts

Joanna L. Mountain, Senior Director of Research
23andMe, Inc., Mountain View, California

Over the past 500 years, North America has been the site of ongoing mixing of Native Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave trade), shaping the early history of what became the United States. We studied the genetic ancestry of 5,269 self-described African Americans, 8,663 Latinos, and 148,789 European Americans who are 23andMe customers and show that the legacy of these historical interactions is visible in the genetic ancestry of present-day Americans. We document pervasive mixed ancestry and asymmetrical male and female ancestry contributions in all groups studied. We show that regional ancestry differences reflect historical events, such as early Spanish colonization, waves of immigration from many regions of Europe, and forced relocation of Native Americans within the US. This study sheds light on the fine-scale differences in ancestry within and across the United States and informs our understanding of the relationship between racial and ethnic identities and genetic ancestry.

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Genetic diversity of Sub-Saharan Africa revealed

Posted in Africa, Articles, Health/Medicine/Genetics, Media Archive on 2014-12-16 02:40Z by Steven

Genetic diversity of Sub-Saharan Africa revealed

BBC News
2014-12-04

Rebecca Morelle, Science Correspondent

Scientists have completed a comprehensive study of genetic diversity in Sub-Saharan Africa.

The African Genome Variation Project analysed the DNA of 1,800 people living across the continent.

The data is helping scientists to understand how susceptibility to disease varies across the region and has provided more insight into how populations have moved within Africa.

The research is published in the journal Nature.

Until now, most studies examining genetic risk factors for disease have focused on Europe. Little has been known about Africa, the most genetically diverse region in the world.

Dr Manj Sandhu, from the Wellcome Trust Sanger Institute and the University of Cambridge, said: “We originally set out to look at chronic diseases in Africa, and one strategy to understand the causes of those diseases is to look at the underlying genetic susceptibility.

“But to do that, you need a pretty good grasp of the variation in genomes across the region, but we realised that information wasn’t available.”…

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Race Unmasked: Biology and Race in the Twentieth Century

Posted in Books, Health/Medicine/Genetics, History, Media Archive, Monographs on 2014-12-12 21:18Z by Steven

Race Unmasked: Biology and Race in the Twentieth Century

Columbia University Press
September 2014
304 pages
Hardcover ISBN: 9780231168748
E-book ISBN: 9780231537995

Michael Yudell, Associate Professor, Interim Chair, Community Health and Prevention
Drexel University School of Public Health, Philadelphia, Pennsylvania

Foreword by J. Craig Venter

Race, while drawn from the visual cues of human diversity, is an idea with a measurable past, an identifiable present, and an uncertain future. The concept of race has been at the center of both triumphs and tragedies in American history and has had a profound effect on the human experience. Race Unmasked revisits the origins of commonly held beliefs about the scientific nature of racial differences, examines the roots of the modern idea of race, and explains why race continues to generate controversy as a tool of classification even in our genomic age.

Surveying the work of some of the twentieth century’s most notable scientists, Race Unmasked reveals how genetics and related biological disciplines formed and preserved ideas of race and, at times, racism. A gripping history of science and scientists, Race Unmasked elucidates the limitations of a racial worldview and throws the contours of our current and evolving understanding of human diversity into sharp relief.

Contents

  • Foreword by J. Craig Venter
  • Acknowledgments
  • Introduction
  • 1. A Eugenic Foundation
  • 2. Charles Davenport and the Biology of Blackness
  • 3. Eugenics in the Public’s Eye
  • 4. The National Research Council and the Scientific Study of Race
  • 5. Coloring Race Difference
  • 6. Biology and the Problem of the Color Line
  • 7. Race and the Evolutionary Synthesis
  • 8. Consolidating the Race Concept in Biology
  • 9. Challenges to the Race Concept
  • 10. Naturalizing Racism: The Controversy Over Sociobiology
  • 11. Race in the Genomic Age
  • Epilogue: Dobzhansky’s Paradox and the Future of Racial Research
  • Notes
  • Bibliography
  • Index
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Rethinking 21st Century Racism on the Way Home

Posted in Articles, Health/Medicine/Genetics, Media Archive, Social Science, United States on 2014-12-12 02:17Z by Steven

Rethinking 21st Century Racism on the Way Home

GeneWatch
Council for Responsible Genetics
Volume 27, Issue 2 (May-July 2014)

Victoria Massie, Ph.D. Candidate
Department of Anthropology
University of California, Berkeley

Returning home from fieldwork can be difficult when you find yourself caught between an unintended call back to your project and the impending reality that home has lost its capacity to act as sanctuary. That was at least the situated liminality I encountered in the John F. Kennedy International Airport on July 16, 2013. Fresh off of a flight from Belgium after leaving Cameroon, I met America at a crossroads. It had been a little over 48 hours since the news had circulated around the country, and the world, that self-proclaimed neighborhood watchman-turned-vigilante George Zimmerman was found not guilty for stalking and shooting in the chest at point-blank range a young 17 year-old boy, Trayvon Martin, who was simply returning home after buying some skittles and iced tea.

Indeed, since I had left it in May, America had proven itself audacious and arrogant in ways that I could not stomach. To think it had only been a few days earlier that I met with a young Cameroonian woman at a café in downtown Douala to inform her that, despite the election of Barack Obama, America still has yet to fully confront the legacy of racism. That it still haunts those bodies whose skin does not prove bright enough to mirror the clouds. That despite her dreams of changing the world through medicine, America was not necessarily likely to welcome her, at least not with open arms. That she, like me, like my family, like many of my friends, would come to find herself engaging in the fight of her life in the pursuit of her happiness away from home.

As I sat in the waiting area, anxious to board my final flight to San Francisco, I doubted my advice had been marked by anything more than naïveté. After all, surrounded by television screens in every direction, all of which seemed to be tuned in to the same program on CNN, I listened as one of the jurors, protected by the veil of anonymity in a world marked by surveillance, echoed the President’s official statement that the verdict was justice served.

I was not thirsty enough to swallow the audacious idea that one could condone the possibility that it could ever be rational to consume black life, my life, with all of its innocent willingness to exist, with impunity…

…Much work has been done to discuss the problematic ways American racial categories are, without even a second thought, being re-inscribed into the genome through what has come to be called genetic “ancestry.” And though its applications were first limited to the field of biomedicine, the burgeoning field of direct-to-consumer DNA tests has turned ancestry testing into the latest American pastime. From spit-parties at New York fashion week to Baptist church services and family reunion backyard barbeques, it seems most Americans know someone who has taken a genetic ancestry test, or have done so themselves. While I was working at the Center for Genetics and Society in Berkeley this summer, the director, Marcy Darnovsky, shared with me her recent encounter with a woman in a checkout line in Trader Joe’s. With a voice that carried across the aisles, the woman standing in front of her announced to a friend – and, unintentionally, the rest of the grocery store – the various percentages of African, European, Asian and Native American ancestry seamlessly replicating within her…

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The African Genome Variation Project shapes medical genetics in Africa

Posted in Africa, Articles, Health/Medicine/Genetics, Media Archive on 2014-12-11 02:16Z by Steven

The African Genome Variation Project shapes medical genetics in Africa

Nature: International Weekly Journal of Science
Published online: 2014-12-03
15 pages
DOI: 10.1038/nature13997

Deepti Gurdasani
Wellcome Trust Sanger Institute
Genome Campus
Hinxton, Cambridge, United Kingdom

et. al.

Given the importance of Africa to studies of human origins and disease susceptibility, detailed characterization of African genetic diversity is needed. The African Genome Variation Project provides a resource with which to design, implement and interpret genomic studies in sub-Saharan Africa and worldwide. The African Genome Variation Project represents dense genotypes from 1,481 individuals and whole-genome sequences from 320 individuals across sub-Saharan Africa. Using this resource, we find novel evidence of complex, regionally distinct hunter-gatherer and Eurasian admixture across sub-Saharan Africa. We identify new loci under selection, including loci related to malaria susceptibility and hypertension. We show that modern imputation panels (sets of reference genotypes from which unobserved or missing genotypes in study sets can be inferred) can identify association signals at highly differentiated loci across populations in sub-Saharan Africa. Using whole-genome sequencing, we demonstrate further improvements in imputation accuracy, strengthening the case for large-scale sequencing efforts of diverse African haplotypes. Finally, we present an efficient genotype array design capturing common genetic variation in Africa.

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