Review of Jonathan Kahn, Race in a Bottle: The Story of BiDil and Racialized Medicine in the Post-Genomic Age

Posted in Articles, Book/Video Reviews, Health/Medicine/Genetics, Media Archive, Politics/Public Policy, United States on 2016-10-28 19:21Z by Steven

Review of Jonathan Kahn, Race in a Bottle: The Story of BiDil and Racialized Medicine in the Post-Genomic Age

The American Journal of Bioethics
Volume 15, 2015 – Issue 10
pages W4-W5
DOI: 10.1080/15265161.2015.1067339

Nathan Nobis, Associate Professor of Philosophy
Morehouse College, Atlanta, Georgia

In 2005 the Food and Drug Administration (FDA) approved the drug BiDil, a combination of two generic vasodilators (hence bi-dil), with specific indication to treat heart failure in black patients. The drug was approved largely on the basis of results from a small clinical trial of only self-identified black patients.

Obviously, however, if a drug works with a particular population, that gives no indication that drug will work only with that population or have unique benefits solely for that population: The drug might work for anyone, of any population, and so works well for a subpopulation. So there is some mystery why BiDil was approved, with this specific indication, on this basis. In Race in a Bottle: The Story of BiDil and Racialized Medicine in the Post-Genomic Age, law professor and historian Jonathan Kahn investigates this mystery.

BiDil’s developers argued that there must be some latent genetic explanation for the drug’s success with black patients—this argument underlies their claim that BiDil uniquely benefits black people. They suggest that race serves as useful surrogate or proxy until further genetic information is revealed.

A major goal of the book is to rebut this explanation. Kahn argues that, according to the best science (and philosophical theorizing about the nature of races), there is no genetic basis for race: There are no unique genes that classify (those who many see as) white people as white and (those who many see as) black people as black, and so on. Race-specific efficacy in drugs is therefore unlikely and dubious, given the lack of race-specific biological mechanisms needed for these drugs to perform as promised.

What role should race play in medicine and public health, then? While Kahn provides positive proposals here, another of his major goals is to argue that race-specific drugs have the (typically unintended) negative consequence of undermining potentially effective projects to address racial health disparities. If we believe that health inequalities are, at root, an unfortunate consequence of genetics and biology—and not a consequence of unfair social, political, and educational opportunities, environmental quality, inequalities in health care access, racism in health care, and other social causes—then there is little reason to focus on these very challenging and demanding issues of justice and the distribution of health-related social, educational, and vocational goods: Just take a pill! But if the pills don’t work, and they lead us to ignore or downplay strategies that will work, then the drugs wrongfully distract—to the detriment of those the drugs were developed to benefit.

In what follows, I briefly summarize the book’s introduction, eight chapters, and very helpful “Conclusions and Recommendations,” and comment on some of the main issues of each chapter…

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Congress Should Tell the OMB to Stop Dividing the Country

Posted in Articles, Census/Demographics, Media Archive, Politics/Public Policy, United States on 2016-10-27 14:13Z by Steven

Congress Should Tell the OMB to Stop Dividing the Country

The Heritage Foundation
Issue Brief #4614 on Office Of Management And Budget
2016-10-11

Mike Gonzalez, Senior Fellow
The Kathryn and Shelby Cullom Davis Institute for National Security and Foreign Policy

On the first day of Congress’s recess, the Obama Administration recommended the most sweeping changes to the nation’s official racial and ethnic categories in decades. The two most significant proposals were creating a new ethno/racial group for people who originate from the Middle East and North Africa (MENA) and taking from those who identify as Hispanic the option to identify their race. The Office of Management and Budget (OMB) Notice asked for comments to be submitted within a month—the shortest window possible—for what it described as a “limited revision” of data collection practices. Far from limited, the proposals would have long-term consequences for how one-fifth of all Americans are defined demographically and would create more societal conflict over racial preferences and political gerrymandering. The American people deserve more than a month to debate such significant changes, and Congress must weigh in.

Racial Reclassifications

The Obama Administration’s proposal would mean that, as early as the 2020 Census, those of Middle East and North African origin, who have been classified as white for over a century, would now be reclassified as a single and unified minority group. At the same time, people of Latin American or Iberian origins would no longer be able to declare whether they are also white, black, or another race, effectively making “Hispanic” their only racial identifier. This would be the biggest change to the nation’s official demography since OMB created Hispanics in 1977 and the Census divided the country into an ethno-racial pentagon that also included White, Black, Asian and American Indian in 1980. The Clinton Administration tried to create MENA and make Hispanics “a racial designation rather than an ethnicity” but failed, settling instead for the addition of “Native Hawaiian or Other Pacific Islander” as a sixth group in 1997, the last major change…

Read the entire article here.

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Standards for Maintaining, Collecting, and Presenting Federal Data on Race and Ethnicity

Posted in Articles, Census/Demographics, Media Archive, Politics/Public Policy, United States on 2016-10-24 17:33Z by Steven

Standards for Maintaining, Collecting, and Presenting Federal Data on Race and Ethnicity

Federal Register: The Daily Journal of the United States Government
A Notice by the Management and Budget Office on 09/30/2016
2016-09-30
4 pages

Howard A. Shelanski, Administrator
Office of Information and Regulatory Affairs

AGENCY:
Executive Office of the President, Office of Management and Budget (OMB).

ACTION:
Review and Possible Limited Revision of OMB’s Statistical Policy Directive on Standards for Maintaining, Collecting, and Presenting Federal Data on Race and Ethnicity.

SUMMARY:
The Standards for Maintaining, Collecting, and Presenting Federal Data on Race and Ethnicity were last revised in 1997 (62 FR 58782, Oct. 30, 1997; see https://www.whitehouse.gov/omb/fedreg_1997standards). Since these revisions were implemented, much has been learned about how these standards have improved the quality of Federal information collected and presented on race and ethnicity. At the same time, some areas may benefit from further refinement. Accordingly, OMB currently is undertaking a review of particular components of the 1997 standard: The use of separate questions measuring race and ethnicity and question phrasing; the classification of a Middle Eastern and North African group and reporting category; the description of the intended use of minimum reporting categories; and terminology used for race and ethnicity classifications. OMB’s current review of the standard is limited to these areas. Specific questions appear under the section, “Issues for Comment.”

DATES:
Comments on the review and possible limited revisions to OMB’s Standards for Maintaining, Collecting, and Presenting Federal Data on Race and Ethnicity detailed in this notice must be in writing. To ensure consideration of comments, they must be received no later than [30 days from the publication of this notice]. Please be aware of delays in mail processing at Federal facilities due to increased security. Respondents are encouraged to send comments electronically via email, or http://www.regulations.gov (discussed in ADDRESSES below)…

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Collection of demographic data regarding multiracial identification.

Posted in Articles, Census/Demographics, Law, Media Archive, Politics/Public Policy, United States on 2016-10-22 23:08Z by Steven

Collection of demographic data regarding multiracial identification.

The New York City Council
Melissa Mark-Viverito, Speaker
2014-11-25 (Passed 2016-11-13)

Int 0551-2014, Version A (2014-11-25)

A Local Law to amend the New York city charter, in relation to the collection of demographic data regarding multiracial identification

Proposed Int. No. 551-A would require the Department of Social Services, the Administration for Children’s Services, the Department of Homeless Services, the Department of Health and Mental Hygiene, the Department for the Aging, the Department of Youth and Community Development, the Department of Education, and any other agencies designated by the Mayor to provide to all persons served by the agency with a demographic information survey that contains an option for multiracial ancestry or ethnic origin. The bill would also require an annual review of all forms from the designated agencies, or any other agency designated by the Mayor, that collect demographic information, are completed by persons seeking services, and are within the administering agencies’ authority to amend. The bill would require all such forms to be amended to contain an option for multiracial ancestry or ethnic origin. Proposed Int. 551-A would also require reporting on the collected data.

Passed (50-0) on 2016-11-13. Enacted (Mayor’s Desk for Signature)

For more information, click here.

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Federal officials may revamp how Americans identify race, ethnicity on census and other forms

Posted in Articles, Census/Demographics, Latino Studies, Media Archive, Politics/Public Policy, United States on 2016-10-16 17:34Z by Steven

Federal officials may revamp how Americans identify race, ethnicity on census and other forms

Pew Research Center
2016-10-04

D’Vera Cohn, Senior Writer/Editor

Federal officials are moving ahead with the most important potential changes in two decades in how the government asks Americans about their racial and Hispanic identity. They include combining separate race and Hispanic questions into one and adding a new Middle East-North Africa category.

If approved by the Office of Management and Budget, the revisions would be made on the 2020 census questionnaire and other federal government surveys or forms. Federal statistics about race and Hispanic identity are used to enforce civil rights laws, assist in political redistricting and provide data for research that compares the status of different groups…

Read the entire article here.

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The way ahead

Posted in Articles, Barack Obama, Economics, Media Archive, Politics/Public Policy, United States on 2016-10-10 00:37Z by Steven

The way ahead

The Economist
2016-10-08

Barack Obama, President of The United States

America’s president writes for us about four crucial areas of unfinished business in economic policy that his successor will have to tackle

WHEREVER I go these days, at home or abroad, people ask me the same question: what is happening in the American political system? How has a country that has benefited—perhaps more than any other—from immigration, trade and technological innovation suddenly developed a strain of anti-immigrant, anti-innovation protectionism? Why have some on the far left and even more on the far right embraced a crude populism that promises a return to a past that is not possible to restore—and that, for most Americans, never existed at all?

It’s true that a certain anxiety over the forces of globalisation, immigration, technology, even change itself, has taken hold in America. It’s not new, nor is it dissimilar to a discontent spreading throughout the world, often manifested in scepticism towards international institutions, trade agreements and immigration. It can be seen in Britain’s recent vote to leave the European Union and the rise of populist parties around the world.

Much of this discontent is driven by fears that are not fundamentally economic. The anti-immigrant, anti-Mexican, anti-Muslim and anti-refugee sentiment expressed by some Americans today echoes nativist lurches of the past—the Alien and Sedition Acts of 1798, the Know-Nothings of the mid-1800s, the anti-Asian sentiment in the late 19th and early 20th centuries, and any number of eras in which Americans were told they could restore past glory if they just got some group or idea that was threatening America under control. We overcame those fears and we will again…

Read the entire article here.

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The “Birther” Movement: Whites Defining Black

Posted in Articles, Barack Obama, History, Louisiana, Media Archive, Politics/Public Policy, Slavery, United States, Virginia on 2016-10-08 01:36Z by Steven

The “Birther” Movement: Whites Defining Black

Racism Review
2016-09-18

Dr. Terence Fitzgerald, Clinical Associate Professor
University of Southern California

Hallelujah I say, Hallelujah! Did you hear the news? Did ya? After sending a team of investigators to Hawaii, drawing the attention of the national and international media, and leading an almost six year charge of infesting the mind of those already under the influence of the white racial frame into a catnip type psychological and emotional frenzy; the “benevolent one,” Donald J. Trump, has publically and emphatically acknowledged that our President of the United States of America is—get this, “an American!” Yes it is true. Republican presidential nominee and town jester, Trump on Friday, September 16, 2016 recognized in a public forum for the first time in eight years that President Obama was indeed born in the U.S. After not only leading, but becoming synonymous with what many have described as the “birther movement,” Trump has conceded and given up on furthering the conspiracy theory that our President is not an American citizen.

…One cannot forget the history behind the 1662 Virginia law that in particular focused on the behavior directed toward mixed-race people. The notion of the ‘one drop rule’ was consequently constructed. This legal means for identifying who was Black was judicially upheld as recent as 1985 “when a Louisiana court ruled that a woman with a black great-great-great-great-grandmother could not identify herself as ‘white’ on her passport.” …

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Meritocracy in Obama’s Gilded Age

Posted in Articles, Barack Obama, Campus Life, Media Archive, Politics/Public Policy, United States on 2016-10-07 19:46Z by Steven

Meritocracy in Obama’s Gilded Age

The Chronicle of Higher Education
2016-09-25

Aziz Rana, Professor of Law
Cornell University, Ithaca, New York

The Obama administration’s vision of social mobility in America is bound up with a story about higher education. According to this story, elite colleges and universities are engines of American opportunity. They select the most talented and hardworking people, from across all backgrounds, and provide them with the training to achieve even the most “impossibly big dreams,” as Michelle Obama would say. There is truth to this account. Indeed, Barack Obama’s lived experience speaks to the possibility of meritocratic achievement. He is the multiracial child of a single mother from a middle-class background, who through skill and determination made it to top universities and eventually rose to the highest echelon of political power.

But this familiar story of higher education as a spur to social mobility blinds us to both what is pernicious and what is worth defending about the modern American university…

Read the entire article here.

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Slavery’s legacies

Posted in Articles, Brazil, Caribbean/Latin America, Census/Demographics, History, Media Archive, Politics/Public Policy, Slavery, Social Science on 2016-10-04 00:30Z by Steven

Slavery’s legacies

The Economist
2016-09-10

SÃO PAULO

American thinking about race is starting to influence Brazil, the country whose population was shaped more than any other’s by the Atlantic slave trade

ALEXANDRA LORAS has lived in eight countries and visited 50-odd more. In most, any racism she might have experienced because of her black skin was deflected by her status as a diplomat’s wife. Not in Brazil, where her white husband acted as French consul in São Paulo for four years. At consular events, Ms Loras would be handed coats by guests who mistook her for a maid. She was often taken for a nanny to her fair-haired son. “Brazil is the most racist country I know,” she says.

Many Brazilians would bristle at this characterisation—and not just whites. Plenty of preto (black) and pardo (mixed-race) Brazilians, who together make up just over half of the country’s 208m people, proudly contrast its cordial race relations with America’s interracial strife. They see Brazil as a “racial democracy”, following the ideas of Gilberto Freyre, a Brazilian sociologist who argued in the 1930s that race did not divide Brazil as it did other post-slavery societies. Yet the gulf between white Brazilians and their black and mixed-race compatriots is huge…

…Of the 12.5m Africans trafficked across the Atlantic between 1501 and 1866, only 300,000-400,000 disembarked in what is now the United States. They were quickly outnumbered by European settlers. Most whites arrived in families, so interracial relationships were rare. Though white masters fathered many slave children, miscegenation was frowned upon, and later criminalised in most American states.

As black Americans entered the labour market after emancipation, they threatened white incomes, says Avidit Acharya of Stanford University. “One drop” of black blood came to be seen as polluting; laws were passed defining mixed-race children as black and cutting them out of inheritance (though the palest sometimes “passed” as white). Racial resentment, as measured by negative feelings towards blacks, is still greater in areas where slavery was more common. After abolition, violence and racist legislation, such as segregation laws and literacy tests for voters, kept black Americans down.

But these also fostered solidarity among blacks, and mobilisation during the civil-rights era. The black middle class is now quite large. Ms Loras would not seem anomalous in any American city, as she did in São Paulo…

…Both black and white Brazilians have long considered “whiteness” something that can be striven towards. In 1912 João Baptista de Lacerda, a medic and advocate of “whitening” Brazil by encouraging European immigration, predicted that by 2012 the country would be 80% white, 3% mixed and 17% Amerindian; there would be no blacks. As Luciana Alves, who has researched race at the University of São Paulo, explains, an individual could “whiten his soul” by working hard or getting rich. Tomás Santa Rosa, a successful mid-20th-century painter, consoled a dark-skinned peer griping about discrimination, saying that he too “used to be black”.

Though only a few black and mixed-race Brazilians ever succeeded in “becoming white”, their existence, and the non-binary conception of race, allowed politicians to hold up Brazil as an exemplar of post-colonial harmony. It also made it harder to rally black Brazilians round a hyphenated identity of the sort that unites African-Americans. Brazil’s Unified Black Movement, founded in 1978 and inspired by militant American outfits such as the Black Panthers, failed to gain traction. Racism was left not only unchallenged but largely unarticulated.

Now Brazil’s racial boundaries are shifting—and in the opposite direction to that predicted by Baptista de Lacerda. After falling from 20% to 5% between 1872 and 1990, the share of self-described pretos edged up in the past quarter-century, to 8%. The share of pardos jumped from 39% in 2000 to 43% in 2010. These increases are bigger than can be explained by births, deaths and immigration, suggesting that some Brazilians who used to see themselves as white or pardo are shifting to pardo or preto. This “chromatographic convergence”, as Marcelo Paixão of the University of Texas, in Austin, dubs it, owes a lot to policy choices…

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White House wants to add new racial category for Middle Eastern people

Posted in Articles, Census/Demographics, Media Archive, Politics/Public Policy, United States on 2016-10-02 00:30Z by Steven

White House wants to add new racial category for Middle Eastern people

USA Today
2016-10-01

Gregory Korte, White House Reporter

WASHINGTON — The White House is putting forward a proposal to add a new racial category for people from the Middle East and North Africa under what would be the biggest realignment of federal racial definitions in decades.

If approved, the new designation could appear on census forms in 2020 and could have far-reaching implications for racial identity, anti-discrimination laws and health research.

Under current law, people from the Middle East are considered white, the legacy of century-old court rulings in which Syrian Americans argued that they should not be considered Asian — because that designation would deny them citizenship under the 1882 Chinese Exclusion Act. But scholars and community leaders say more and more people with their roots in the Middle East find themselves caught between white, black and Asian classifications that don’t fully reflect their identities…

Read the entire article here.

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