Instituto Cervantes holds forum on genetic diversity in the Philippines

Posted in Anthropology, Articles, Media Archive on 2012-07-28 23:27Z by Steven

Instituto Cervantes holds forum on genetic diversity in the Philippines

GMA News Online
Quezon City, Philippines
2012-07-24

On Tuesday, July 24, Instituto Cervantes presents “Todos somos mestizos: A Topogenetic Atlas of the Philippines,” a forum on the genetic make-up of Filipinos all over the archipelago. The talk will be led by Filipino anthropologist Fernando Zialcita, Ph.D. and Spanish Biology professor, Antonio González-Martín, Ph.D., who is currently in the country to conduct an ongoing project funded by the Goverment of Spain.

The forum’s title, which roughly translates to ”We Are All a Mix,” is a prelude to the subject matter of the genetic diversity of Filipinos originating from different parts of the country. Dr. González-Martín will reveal for the very first time a rough approximation of the genetic make-up of the Filipino people. Why did he choose the Philippines? “Aside from the fact that the Philippines has an extremely rich demographic history, these islands are key to explain the expansion of human beings in the Austronesian region,” says González-Martín…

Read the entire article here.

Tags: , , ,

Pre-Hispanic Mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico

Posted in Anthropology, Articles, Caribbean/Latin America, Media Archive, Mexico on 2009-12-30 01:18Z by Steven

Pre-Hispanic Mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico

American Journal of Physical Anthropology
Volume 139 Issue 3
Pages 284 – 294
Published Online: 2009-01-12

Rodrigo Rubi-Castellanos
Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, (CUCiénega-UdeG), Ocotlán, Jalisco, México

Gabriela Martínez-Cortés
Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, (CUCiénega-UdeG), Ocotlán, Jalisco, México

José Francisco Muñoz-Valle
Instituto de Investigación en Reumatología y del Sistema Músculo-Esquelético, Centro Universitario de Ciencias de la Salud (CUCS-UdeG), Guadalajara, Jalisco, México

Antonio González-Martín
Departamento de Zoología y Antropología Física, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain

Ricardo M. Cerda-Flores
Departamento de Genética de Poblaciones y Bioinformática, Centro de Investigación Biomédica del Noreste (CIBN-IMSS), Monterrey, Nuevo León, México

Manuel Anaya-Palafox
Laboratorio de Genética Forense, Instituto Jalisciense de Ciencias Forenses (IJCF), Tlaquepaque, Jalisco, México

Héctor Rangel-Villalobos
Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, (CUCiénega-UdeG), Ocotlán, Jalisco, México

Rodrigo Rubi-Castellanos and Héctor Rangel-Villalobos contributed equally to this work.

Over the last 500 years, admixture among Amerindians, Europeans, and Africans, principally, has come to shape the present-day gene pool of Mexicans, particularly Mestizos, who represent about 93% of the total Mexican population. In this work, we analyze the genetic data of 13 combined DNA index system-short tandem repeats (CODIS-STRs) in 1,984 unrelated Mestizos representing 10 population samples from different regions of Mexico, namely North, West, Central, and Southeast. The analysis of molecular variance (AMOVA) test demonstrated low but significant differentiation among Mestizos from different regions (FST = 0.34%; P = 0.0000). Although the spatial analysis of molecular variance (SAMOVA) predicted clustering Mestizo populations into four well-delimited groups, the main differentiation was observed between Northwest when compared with Central and Southeast regions. In addition, we included analysis of individuals of Amerindian (Purepechas), European (Huelva, Spain), and African (Fang) origin. Thus, STRUCTURE analysis was performed identifying three well-differentiated ancestral populations (k = 3). STRUCTURE results and admixture estimations by means of LEADMIX software in Mestizo populations demonstrated genetic heterogeneity or asymmetric admixture throughout Mexico, displaying an increasing North-to-South gradient of Amerindian ancestry, and vice versa regarding the European component. Interestingly, this distribution of Amerindian ancestry roughly reflects pre-Hispanic Native-population density, particularly toward the Mesoamerican area. The forensic, epidemiological, and evolutionary implications of these findings are discussed herein.

Tags: , , , , , , , , , ,